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Table 4 Relationship between genotype frequency and determinants

From: Association between the single-nucleotide polymorphism (rs1030868) variant in matrix metallopeptidase 2 gene and the development of lymphedema

Variable

AA (1)

(n = 23)

GA (2)

(n = 239)

GG (3)

(n = 18)

P value

Age/years

42.39 ± 13.2

44.58 ± 15.1

46.33 ± 12.9

= 0.686*

P value**

1 vs. 2 = 0.497

2 vs 3 = 0.628

1 vs. 3 = 0.397

Sex

   

= 0.575***

 Female

16 (69.6%)

141 (59%)

10 (55.6%)

 Male

7 (30.4%)

98 (41%)

8 (44.4%)

Severity (cases only)

(n = 16)

(n = 67)

(n = 10)

 

 Stage I

0 (0%)

5 (7.5%)

0 (0%)

= 0.007$

 Stage II

0 (0%)

11 (16.4%)

2 (20%)

 Stage III

0 (0%)

8 (11.9%)

2 (20%)

 Stage IV

3 (18.8%)

20 (29.9%)

2 (20%)

 Stage V

1 (6.3%)

10 (14.9%)

2 (20%)

 Stage VI

9 (56.3%)

8 (11.9%)

2 (20%)

 Stage VII

3 (18.8%)

5 (7.5%)

0 (0%)

  1. *One-way ANOVA test was used to compare means between groups
  2. **Post hoc test was used for Pairwise Comparisons
  3. ***Chi-square test was used to compare the frequency distribution
  4. $Monte Carlo exact test was used to compare the frequency distribution