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Fig. 2 | Egyptian Journal of Medical Human Genetics

Fig. 2

From: Metformin reduces the cellular DNA repair capacity and enhances the effect of curcumin on the induction of apoptosis in AGS gastric cancer cells

Fig. 2

Combination of 0.625 mM metformin and 1 μM curcumin inhibits DNA repair genes expression in AGS cell line. Alterations in the expression of genes involved in DNA repair were measured using real-time qPCR after 72-h treatments with metformin, curcumin, and their combination. Graphs represent mean ± SEM for three independent experiments conducted in triplicates. Statistical analysis was performed using one-way analysis of variance (ANOVA) and Duncan's post hoc test. In each panel, similar letters indicate no statistically significant difference. All experiments were performed independently in triplicate

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