Table 3 Genotype and allele frequencies of the five studied polymorphisms in FGR and controls
Polymorphism | FGR n (%) | HWE*χ2 (P value) | Control n (%) | HWE*χ2 (P value) |
|---|---|---|---|---|
MTHFR 677C > T | n = 46 | n = 55 | ||
CC | 33 (71.7) | 0.71 (0.7) | 29 (52.7) | 0.003 (0.998) |
CT | 11 (23.9) | 22 (40) | ||
TT | 2 (4.4) | 4(7.3) | ||
C | 77 (83.7) | 80 (72.7) | ||
T | 15 (16.3) | 30 (27.3) | ||
MTRR 66A > G | n = 44 | n = 56 | ||
AA | 7 (15.9) | 0.59 (0.74) | 9 (16.1) | 4.62 (0.1) |
AG | 18 (40.9) | 36 (64.3) | ||
GG | 19 (43.2) | 11 (19.6) | ||
A | 32 (36.4) | 54 (48.2) | ||
G | 56 (63.6) | 58 (51.8) | ||
MTR 2756A > G | n = 43 | n = 56 | ||
AA | 29 (67.4) | 0.27 (0.87) | 30 (53.6) | 2.71 (0.26) |
AG | 12 (27.9) | 25 (44.6) | ||
GG | 2 (4.7) | 1 (1.8) | ||
A | 70 (81.4) | 85 (75.9) | ||
G | 16 (18.6) | 27 (24.1) | ||
AGT 704T > C | n = 42 | n = 55 | ||
TT | 11 (26.2) | 0.11 (0.95) | 7 (12.7) | 0.34 (0.84) |
TC | 22 (52.4) | 28 (50.9) | ||
CC | 9 (21.4) | 20 (36.4) | ||
T | 44 (52.4) | 42 (38.2) | ||
C | 40 (47.6) | 68 (61.8) | ||
VEGFA 634C > G | n = 45 | n = 51 | ||
CC | 9 (20) | 1.25 (0.54) | 8 (15.7) | 0.3 (0.86) |
CG | 18 (40) | 22 (43.1) | ||
GG | 18 (40) | 21 (41.2) | ||
C | 36 (40) | 38 (37.3) | ||
G | 54 (60) | 64 (62.7) |