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Table 4 Association of five studied polymorphisms with FGR susceptibility

From: Association of maternal genetic polymorphisms with fetal growth restriction syndrome in Russian pregnant women from Rostov region

Polymorphism

OR (95% CI)

χ2

P value

MTHFR 677C > T

CC

2.28 (1–5.23)

3.82

0.149

CT

0.47 (0.2–1.12)

TT

0.58 (0.1–3.32)

C

1.925 (0.96–3.85)

0.195

0.659

T

0.519 (0.26–1.04)

MTRR 66A > G

AA

1.01 (0.34–2.96)

7.396

0.025*

AG

0.37 (0.17–0.84)

GG

3.18 (1.31–7.72)

A

0.61 (0.35–1.1)

2.824

0.093

G

1.63 (0.92–2.88)

MTR 2756A > G

AA

1.8 (0.79–4.10)

3.267

0.196

AG

0.48 (0.21–1.12)

GG

2.68 (0.24–30.61)

A

1.39 (0.69–2.78)

0.866

0.352

G

0.72 (0.36–1.44)

AGT 704T > C

TT

2.43 (0.85–6.95)

4.113

0.128

TC

1.06 (0.48–2.37)

CC

0.48 (0.19–1.2)

T

1.78 (1.002–3.17)

3.891

0.049*

C

0.58 (0.32–0.998)

VEGFA 634C > G

CC

1.34 (0.47–3.84)

0.316

0.854

CG

0.88 (0.39–1.98)

GG

0.95 (0.42–2.16)

C

1.12 (0.63–2.01)

0.152

0.697

G

0.89 (0.5–1.6)

  1. *P value < 0.05; χ2: chi-square; significant statistical values are shown in bold