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Egyptian Journal of Medical Human Genetics

Table 5 Best predictive gene–gene interaction models identified by MDR analysis

From: Association of maternal genetic polymorphisms with fetal growth restriction syndrome in Russian pregnant women from Rostov region

Locus model

Genes

Training balance accuracy

Testing balance accuracy

CVC consistency

Sensitivity

Specificity

χ2 (P value)

Three

VEGFA 634C > G

MTRR 66A > G AGT 704T > C

0.7073

0.6513

9/10

0.8571

1.0

17.6786 (0.0001)

Four

VEGFA 634C > G

MTRR 66A > G AGT 704T > C

MTR 2756A > G

0.6546

-

7/10

1

1

11.0 (0.0009)

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